Meet AMPK: The Energy Switch You’ve Likely Not Heard of But Use Every Day

Most people outside the medical or research world probably aren’t familiar with AMP-activated protein kinase, or AMPK. But it influences how you experience every day of your life, like how steady your energy levels feel, how easily your body shifts between storing and using fuel, and how effectively your cells recover from stress and damage. Think of it this way: AMPK sets the table for long-term metabolic health and healthy aging.

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Jacqueline Seymour

Nov 5, 2025

October 27, 2025

Health Coach Tip - Optimize Your Meal Timing

We often focus on what we eat – protein, fiber, antioxidants, macros – but research shows that when we eat may be just as important for health and longevity.

Gut Health’s Key Role in Longevity: What Hippocrates Knew and Modern Science Confirms

Hippocrates (460–370 BCE), the Greek physician often hailed as the “father of Western medicine,” is best known for his declaration primum non nocere, or, “First, do no harm”. Whether he uttered those exact words is uncertain, but their spirit has anchored medical ethics through the centuries. Also attributed to him, ‘All disease begins in the gut,’ feels especially pertinent today. Again, the exact phrase may be apocryphal, but the underlying insight lives in his teachings. As modern science expands our understanding of how trillions of microbes in our intestines influence our immunity, metabolism, mood, and aging, I see Hippocrates’ intuition in a new and more profound light. Revisiting that ancient medical tradition helps us think about health and longevity in a more integrative and holistic way, ideally helping us to enhance both.

How Muscles Remember — and Regain — Lost Strength

Taking an unexpected break from fitness due to illness or injury? Don’t stress — your strength can return faster than you think.

Health Coach Tip - Preserve the Best of the Fall Harvest

As we move deeper into fall, the farmer’s market is overflowing with hearty, colorful produce — apples, squash, root vegetables, and leafy greens. It’s the perfect time to make the most of the season’s bounty and prepare nourishing foods to enjoy through the colder months ahead.

Heat Shock Proteins: The Under-the-Radar Longevity Booster Worth Cultivating

Heat shock proteins – don’t let the odd name fool you. The phrase sounds as if we’re talking about proteins that are suffering from too much heat exposure, and that can’t be good. And, in a way, that’s actually not too far off. Heat shock proteins, or HSPs, are a special class of proteins that adapt to the stresses of living, including but by no means limited to exposure to heat, by becoming extra-resilient. In fact, they become so resilient, they’re able to help ordinary proteins repair themselves when they’re subjected to those same pressures. Pretty cool, eh?

All (Adult) Vaginas Need Estrogen

Why most adult vaginas need estrogen brought to you by Dr. Amy Killen.

Health Coach Tip – Prep For A Healthier Halloween

October is the month of candy. Halloween brings endless bowls of M&Ms, Reese’s Peanut Butter Cups, and Candy Corn — all filled with sugar, artificial flavors, food dyes, GMO cornstarch, and other scary ingredients! But with a little planning, you can enjoy the season without the sugar crash (or the junk). Here are some fun, healthier alternatives that are just as delicious — and way better for you.

More than Just Jet-Lag Helper: How Mighty Melatonin May Guard Your Brain, Mitochondria, and Longevity

Chances are, you’ve probably taken melatonin from time to time when struggling with sleep or crisscrossing time zones. The idea is that as evening falls, your primary energy hormone cortisol drops and melatonin goes up, cueing the body for sleep, which is why some have dubbed melatonin “the hormone of darkness.” Well, guess what? Melatonin is stepping into the spotlight to help aging brains The latest research has revealed that it’s produced in the mitochondria, the cell powerplants, in a number of your organs, and that it’s involved a wide range of important physiological processes, some of which have nothing directly to do with sleep – and more to do with brain health over the long haul.

Healthy Aging